94 Results for "

Garcinia cowa Roxb.

" in MedChemExpress (MCE) Product Catalog:
Products (94)

94 Results for "Garcinia cowa Roxb." in MCE Product Catalog:

9
Engeletin
Engeletin
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9 Publications Verification
Cat. No.: HY-N0436
CAS No.: 572-31-6
Category:  

Plants Flavanonols Liliaceae Flavonoids Microorganisms Phenols Polyphenols Smilacis Glabrae Rhizoma Disease Research Fields Inflammation/Immunology

Target:  

NF-κB

Engeletin is a flavanonol glycoside isolated from Smilax glabra Roxb. , inhibits NF-κB signaling-pathway activation, and possesses anti-inflammatory, analgesic, diuresis, detumescence, and antibiosis effects.
6
Gambogic Acid
Gambogic Acid
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6 Cited Publications
Cat. No.: HY-N0087
CAS No.: 2752-65-0
Synonyms: Beta-Guttiferrin
Category:  

Natural Products Guttiferae Plants Garcinia hanburyi Hook. f. Disease Research Fields Cancer

Target:  

Bcl-2 Family Autophagy

Gambogic Acid (Beta-Guttiferrin) is derived from the gamboges resin of the tree Garcinia hanburyi. Gambogic Acid (Beta-Guttiferrin) inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50s of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM and 0.79 μM.
5
Garcinol
Garcinol
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5 Cited Publications
Cat. No.: HY-107569
CAS No.: 78824-30-3
Pureté:  ≥99.0%
Category:  

Guttiferae Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology Garcinia indica

Target:  

Cholinesterase (ChE) Histone Acetyltransferase Apoptosis Endogenous Metabolite

Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 μM and 7.39 μM, respectively . Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity .
4
Nitidine chloride
Nitidine chloride
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4 Cited Publications
Cat. No.: HY-N0498
CAS No.: 13063-04-2
Category:  

Alkaloids Rutaceae Zanthoxylum nitidum (Roxb.) DC. Plants Disease Research Fields Isoquinoline Alkaloids Inflammation/Immunology

Target:  

Parasite Apoptosis STAT Topoisomerase ERK FAK p38 MAPK NF-κB

Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis, inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A, ERK and c-Src/FAK associated signaling pathway, also has anti-inflammatory activity. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway .
2
Garcinone C
Garcinone C
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2 Cited Publications
Cat. No.: HY-N6954
CAS No.: 76996-27-5
Category:  

other families Xanthones Garcinia oblongifolia Champ. ex Benth. Guttiferae Phenols Polyphenols Plants Disease Research Fields Cancer

Target:  

ATM/ATR STAT CDK Hedgehog

Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner through inhibition of Hedgehog signaling pathway. Garcinone C is orally active .
1
Hydroxycitric acid tripotassium
Hydroxycitric acid tripotassium
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1 Cited Publications
Cat. No.: HY-W338584
CAS No.: 232281-44-6
Tripotassium hydroxycitrate is an orally active, multi-target, multi-bioactive organic acid. Tripotassium hydroxycitrate activates Nrf2 and its downstream molecule GPX4, increases glutathione levels, and thereby inhibits ferroptosis. Tripotassium hydroxycitrate activates the Nrf2/Keap1 and ACLY/NF-κB signaling pathways, upregulates the activities of antioxidant enzymes such as superoxide dismutase, reduces MDA content, thereby alleviating oxidative stress and renal tubular epithelial cell apoptosis, and improves pulmonary vascular and right ventricular remodeling. Tripotassium hydroxycitrate activates both the AMPK and mTORC1/S6K pathways, triggers the unfolded protein response, arrests the cancer cell cycle, and induces DNA fragmentation .
1
Morellic acid
Morellic acid
0 Images
1 Cited Publications
Cat. No.: HY-N4094
CAS No.: 5304-71-2
Category:  

Natural Products other families Monophenols Phenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Others

Morellic acid is isolated from Garcinia Morella with an antiangiogenic activity .
Phloracetophenone
Phloracetophenone
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Cat. No.: HY-W008226
CAS No.: 480-66-0
Synonyms: 2,4,6-trihydroxyacetophenone; 1-(2,4,6-Trihydroxyphenyl)ethanone
Category:  

Metabolic Disease Plants Curcuma comosa Roxb. Infection other families Ketones, Aldehydes, Acids Phenols Polyphenols Disease Research Fields Zingiberaceae

Target:  

Cytochrome P450 Bacterial Antibiotic

Phloracetophenone (2,4,6-trihydroxyacetophenone) is the aglycone part of acetophenone glycoside obtained from Curcuma comosa Roxb, with cholesterol-lowering activity. Phloracetophenone enhances cholesterol 7α-hydroxylase (CYP7A1) activity . Phloracetophenone stimulats bile secretion mediated through Mrp2 .
Macurin
Macurin
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Cat. No.: HY-N3347
CAS No.: 519-34-6
Synonyms: Maclurin
Category:  

Garcinia lancilimba C. Y. Wu ex Y. H. Li Guttiferae Phenols Polyphenols Plants

Target:  

Others

Macurin is a xanthone that can be isolated from Garcinia lancilimba .
(-)-Hydroxycitric acid lactone
(-)-Hydroxycitric acid lactone
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Cat. No.: HY-N7347
CAS No.: 27750-13-6
Synonyms: Garcinia lactone
Category:  

other families Ketones, Aldehydes, Acids Metabolic Disease Plants Disease Research Fields

Target:  

ATP Citrate Lyase

(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a popular weight loss food supplement. (-)-Hydroxycitric acid lactone is a potent inhibitor of ATP-citrate lyase. (-)-Hydroxycitric acid lactone catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA, limits the availability of acetyl-CoA units required for fatty acid synthesis .
Garcinia cambogia extract
Garcinia cambogia extract
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Cat. No.: HY-N14035
CAS No.: 90045-23-1
Category:  

Natural Products Guttiferae Garcinia cambogia Desr. Plants

Target:  

FABP PPAR

Garcinia cambogia extract is an orally active anti-obesity agent . Garcinia cambogia extract upregulates the gene expression of aP2, SREBP1c, PPARγ2 and C/EBPα. Garcinia cambogia extract reduces the rate of body weight gain, visceral fat accumulation, lipid levels in blood and liver, as well as plasma insulin and leptin levels . Garcinia cambogia extract ameliorates high-fat diet-induced obesity .
9-Hydroxycalabaxanthone
9-Hydroxycalabaxanthone
0 Images
Cat. No.: HY-N2795
CAS No.: 35349-68-9
Synonyms: Xanthone I
Target:  

Parasite Bacterial

Domaines de recherche:  

Infection

9-Hydroxycalabaxanthone (Xanthone I) is a known xanthone isolated from Garcinia mangostana Linn. 9-Hydroxycalabaxanthone has quorum-sensing inhibitory, anti-microbial, and anti-malarial activities (IC50=1.2-1.5 μM) .
Cowaxanthone B
Cowaxanthone B
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Cat. No.: HY-N6248
CAS No.: 212842-64-3
Category:  

Infection other families Xanthones Phenols Polyphenols Plants Disease Research Fields

Target:  

Bacterial

Cowaxanthone B is a xanthone isolated from the fruits of Garcinia cowa. Cowaxanthone B has weak antibacterial activity .
Neosmitilbin
Neosmitilbin
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Cat. No.: HY-N5115
CAS No.: 54081-47-9
Category:  

Flavanonols other families Flavonoids Other Diseases Phenols Polyphenols Plants Disease Research Fields

Target:  

Others

Neosmitilbin is isolated from Garcinia mangostana.
R-30-Hydroxygambogic acid
R-30-Hydroxygambogic acid
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Cat. No.: HY-N10678
CAS No.: 881027-35-6
Category:  

Ketones, Aldehydes, Acids Guttiferae Plants Garcinia hanburyi Hook. f.

Target:  

Others

R-30-Hydroxygambogic acid is polyprenylated xanthone epimer that can be isolated from gamboges of Garcinia hanburyi. R-30-Hydroxygambogic acid shows cytotoxicities to Human Leukemia K562 cell lines of IC50 values of 2.89 and 1.27 μM for K562/R and K562/S, respectively. R-30-Hydroxygambogic acid can be used for the research of cancer .
Velutinam
Velutinam
0 Images
Cat. No.: HY-N16516
CAS No.: 146428-62-8
Category:  

Alkaloids Pyrrole Alkaloids Uvaria grandiflora Roxb. Plants Annonaceae

Target:  

Bacterial

Velutinam is an alkaloid. Velutinam can be isolated from twigs of Uvaria grandiflora Roxb. Velutinam shows antioxidant activity. Velutinam can be used in the research of bacterial infections .
1,3,5,6-Tetrahydroxyxanthone
1,3,5,6-Tetrahydroxyxanthone
0 Images
Cat. No.: HY-N9113
CAS No.: 5084-31-1
Category:  

Flavonoids Guttiferae Hyperlcurn perforatum L. Plants Other Flavonoids

Target:  

Others

1,3,5,6-Tetrahydroxyxanthone is a natural xanthone that can be isolated from Garcinia achachairu Rusby (Clusiaceae) branches. 1,3,5,6-Tetrahydroxyxanthone induces diuresis and saluresis in normotensive and hypertensive rats .
Jaslanceoside B
Jaslanceoside B
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Cat. No.: HY-N16539
CAS No.: 188300-82-5
Category:  

Gastrodia elata Bl. Orchidaceae Plants Saccharides Monosaccharides

Target:  

Others

Jaslanceoside B is a secoiridoid glucoside found in Jasminum lanceolarium Roxb .
Esculentoside B
Esculentoside B
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Cat. No.: HY-N6032
CAS No.: 60820-94-2
Synonyms: Phytolaccoside B
Category:  

Plants Phytolaccaceae Phytolacca americana L.

Target:  

Cholinesterase (ChE) JNK NF-κB Fungal

Esculentoside B (Phytolaccoside B) is a natural product from the roots of Phytolacca acinosa Roxb. Esculentoside B is neurotoxic to zebrafish larvae, and impairs their central nervous system development. Esculentoside B inhibits inflammatory response and has antifungal activity .
1,5-Dihydroxyxanthone
1,5-Dihydroxyxanthone
0 Images
Cat. No.: HY-N8557
CAS No.: 14686-65-8
Category:  

Guttiferae Phenols Polyphenols Plants Garcinia cowa Roxb.

Target:  

Others

1,5-Dihydroxyxanthone (Compound 5) is a xanthone that can be isolated from the root of Garcinia cowa .
Assay Types